Past Grants Summary
Completed research projects and previous funding that have contributed to the BRAIN Lab's mission.
Past Grants
Identification of Distinct Multimodal Biotypes of PTSD Using Data Drive Approach: A Multisite Big Data Study
Grant Number: 1K01MH122774-01
Funding Agency: NIMH | Period: 12/10/2020-12/09/2024
The goal of this project is to utilize a data-driven computational approach and machine learning techniques to identify multimodal neural biomarkers of PTSD and multimodal biotypes of PTSD.
PI: Dr. Zhu | Lab Role: PI
Towards Precision Diagnosis for PTSD Using Multimodal MRI: A multisite "Big Data" Study
Grant Identifier: NARSAD Young Investigator Grant
Funding Agency: NARSAD (Brain & Behavior Research Foundation) | Period: 1/14/2019-7/14/2021
The goal of this Research Project Grant is to utilize multimodal brain features, including structural MRI, resting state functional MRI (rs-fMRI) and diffusion tensor imaging (DTI), and machine-learning, to diagnostically differentiate patients with PTSD from trauma-exposed healthy controls.
PI: Dr. Zhu | Lab Role: PI
Advancing PTSD research using novel multimodal MRI and machine learning
Grant Identifier: Irving Imaging Pilot Award
Funding Agency: Irving Institute for Clinical and Translational Research | Period: 5/1/2017-5/1/2018
The goal of this project is to advance PTSD research by using novel multimodal MRI, and machine learning methods, aiming to identify a neural signature of PTSD, and to examine its utility in predicting diagnosis, functional impairment, and symptom severity.
PI: Dr. Zhu | Lab Role: PI
Statistical method for neural mechanism mediating and moderating cognitive system in Alzheimer's disease and aging research.
Grant Number: R01 AG062578
Funding Agency: NIA | Period: 10/01/2019-10/1/2024
This project focuses on developing statistical methods to understand neural mechanisms in Alzheimer's disease and aging.
PI: Dr. Lee | Lab Role: Data analyst (Dr. Zhu)
A Phase 3 clinical trial on transcendental meditation and Posttraumatic Stress Disorder, suicide, and substance use in veterans
Grant Identifier: David Lynch Foundation Grant
Funding Agency: David Lynch Foundation | Period: 7/1/2022-12/1/2024
This clinical trial investigates the effects of transcendental meditation on PTSD, suicide, and substance use in veterans.
PI: Dr. Neria | Lab Role: Co-Investigator (Dr. Zhu)
Neural, behavioral, and endocrine correlates of trauma among women.
Grant Identifier: Binational Science Foundation Grant
Funding Agency: Binational Science Foundation | Period: 2020-2024
The goal of this project is to bridge existing gaps in understanding of behavioral, neural and endocrine mechanisms linking traumatic events to the development of PTSD in women.
PI: Dr. Helpman | Lab Role: Co-Investigator (Dr. Zhu)
Cognitive and neural Mechanisms of Accelerating Aging in PTSD
Grant Number: R01 MH111596-01
Funding Agency: NIMH | Period: 9/1/2016-8/31/2021
The goal of this R01 Research Project Grant is to understand the biological mechanisms leading to increased rates of aging-associated medical diseases, cognitive decline, and frailty characteristics in older adults with Post Traumatic Stress Disorder (PTSD).
PI: Dr. Rutherford | Lab Role: Co-Investigator (Dr. Zhu)
Cognitive and neural Mechanisms of Accelerating Aging in PTSD (Administrative Supplement)
Grant Number: R01 MH111596-01, Admin Supplement
Funding Agency: NIMH | Period: 8/1/2019-7/30/2022
This administrative supplement supports ongoing research to understand the biological mechanisms of accelerated aging in older adults with PTSD.
PI: Dr. Rutherford | Lab Role: Co-Investigator (Dr. Zhu)
Neural Signature of Fear Overgeneralization in Trauma Exposed Adults
Grant Number: R01MH105355-01A1
Funding Agency: NIMH | Period: 7/1/2015-6/30/2019
The goal of this R01 Research Project Grant is to use fMRI and machine learning analysis among trauma exposed adults and matched controls in order to characterize the neural signature of fear overgeneralization across diagnostic boundaries.
PI: Dr. Neria | Lab Role: Co-Investigator (Dr. Zhu)
Attention bias modification treatments in SAD
Grant Number: R61/R33 MH116089
Funding Agency: NIMH | Period: 7/1/2018-7/1/2023
The present study is an open trial that seeks to examine the feasibility, acceptability, mechanism, and efficacy of a recently developed computer-based therapy in individuals with social anxiety disorder (SAD).
PI: Dr. Schneier | Lab Role: FMRI analyst and data manager (Dr. Zhu)
Trauma Modified Equine Assisted PTSD treatment
Grant Identifier: Mack Foundation Grant
Funding Agency: Mack Foundation | Period: 1/1/2015-12/31/2019
The goal of present study is to test the safety, acceptability and efficacy of a trauma modified equine assisted treatment for war veterans.
PI(s): Dr. Fisher, Dr. Neria | Lab Role: Data Analyst (Dr. Zhu)
Training Program for a Proven Curriculum for Equine-Assisted Therapy for Veterans with PTSD Symptoms
Grant Identifier: Bob Woodroff Foundation Grant
Funding Agency: Bob Woodroff Foundation | Period: 9/24/2019 - 9/23/2020
This project focuses on a training program for equine-assisted therapy for veterans with PTSD.
PI(s): Dr. Fisher, Dr. Neria | Lab Role: Data Analyst (Dr. Zhu)