Neural Correlates of Obesity in Adolescents

Project Overview

This systematic review explores the neural correlates of obesity specifically within adolescent populations. Understanding the brain mechanisms associated with obesity during this critical developmental window is crucial for developing effective prevention and intervention strategies. We aim to synthesize findings from neuroimaging studies examining brain structure, function, and connectivity in relation to weight status and eating behaviors in adolescents.

Key Research Questions

• What structural brain differences are consistently observed in adolescents with obesity compared to healthy-weight peers?
• How does brain response to food cues differ in adolescents with obesity?
• Are there alterations in reward circuitry, cognitive control networks, or interoceptive processing associated with adolescent obesity?
• Do neural correlates predict weight gain trajectories or response to weight management interventions in this age group?

Methodology

We perform a systematic search of major scientific databases for neuroimaging studies (fMRI, sMRI, DTI, PET) focusing on obesity, overweight, BMI, or eating behaviors in adolescent samples (typically ages 10-19). Findings related to brain structure, activation patterns (especially in response to food stimuli), and functional connectivity are extracted and synthesized.

Current Status

The review is ongoing. We are currently screening and extracting data from relevant studies. The final report will summarize the key neural findings related to adolescent obesity, discuss methodological considerations, and highlight areas needing further research.