Functional Brain Connectivity in Trauma

Project Overview

This research investigates how traumatic experiences affect brain network connectivity and function, using advanced neuroimaging techniques to understand the neural mechanisms underlying trauma response and recovery.

Key Research Questions

• How does trauma alter functional connectivity patterns in brain networks?
• Are there specific network disruptions associated with PTSD symptom severity?
• Can functional connectivity serve as a biomarker for trauma exposure or recovery?
• How do brain connectivity changes relate to treatment outcomes?

Methodology

We utilize resting-state and task-based fMRI, along with advanced network analysis techniques (e.g., graph theory, dynamic connectivity analysis), to compare brain connectivity between trauma-exposed individuals (with and without PTSD) and healthy controls.

Current Status

We are actively analyzing data from multiple trauma-related datasets, identifying reliable patterns of connectivity alterations. We are exploring how these patterns predict individual differences in symptom presentation and treatment response.